Working Hours Liver Organ

Working Hours Liver Organ 
Anatomy of the liver
The liver is the largest organ in the body and terkompleks. Liver is also the organ homeostasis. Which plays an important role in metabolic processes in humans and animals. Single organ in maroon is located within the abdominal cavity right. Exactly below the diaphragm.By function. liver including means of excretion. This is because the liver helps kidney function by breaking some of the compounds that are toxic and produce ammonia, urea and uric acid by utilizing nitrogen from amino acids. Solving process toxic compound by the liver is called detoxification.Normal adult human heart has a mass of about 1.4 kg or about 2.5% of body mass.The liver also be an organ of the second largest after the skin. Convex upper surface and below the diaphragm in town, while the lower surface is uneven and shows the curve of fissures transverses. The entire surface covered with the blood vessels in and out of the liver.In the anatomy of the heart is divided into four lobes. Namely the right lobe, left lobe, caudate lobe, and quadrat lobe.Hati also consists of a collection of microscopic units, called lobul that each - each form a hexagon (roughly). Lobul-lobul is a major processing center for the liver. This is where the liver - liver function - functions, such as filter blood and produce bile.            
         There are some cells in the liver including ito cells, Kupffer cells, and cells pit. In this context, according to a source ng yes I read, explained that the cells are located in tissues ito perisinusidal merupak cell with plenty vesicles within the cytoplasm SEC fat very strong. , Thus providing a layer ganda.pada lobe sinusoidal lumen. When the heart in normal conditions, ito cells store vitamin A in order to control the flexibility of the extracellular matrix. Which is in the form with the SEC which is also the flexibility of the lumen of the sinusoid.           
Kupffer cells are tissue macrophages with intrasinusoidal.Ia is endositik and phagocytic ability astounding. Daily Kupffer cells interact with materials that come from the digestive tract containing a bacterial solution and prevent the activation of toxin effects of these compounds in the liver. Exposure to bacterial solution particularly high exposure to PPS, making Kupffer cells do secretion of various sitoksin that trigger inflammatory processes and could lead to injury to the liver.While pit cells are lymphocytes with large granules, such as NK cells that reside hearts. Pit can induce cell death in tumor cells immediately without relying on the expression of the major histocompatibility complex antigens. Pit cell activity can be enhanced by stimulation interveron- ¥. In addition to the liver is still there-ɣѢ T cells, NKT cells.             
           Subsequently explained further that in addition to hepatocytes and nonpenkimal cells, the liver still other types of cells, namely intrahepatic (often called oval cells) and hepatocytes duktural. Regeneration after partial hepatectomy, generally do not involve progenitor cells intrahepatic and extrahepatic stem cells, and depend only on hepatocyte proliferation. But in conditions when the proliferation of hepatocytes blocked or delayed, oval cells that are diarea periportal will undergo proliferation and differentiation into mature hepatocytes. Oval cells is a form of differentiation of progenitor cells that are at the portal area and found when liver injury. Proliferation that occurs in oval cells will form the excretory duct that connects the area where damage to the liver parenchyma to the bile ducts.           
           Meanwhile epimorfin a role morphogens that are found on many epithelial organs. And looks also play a role in the formation of bile duct by hepatic stem cells. After that oval cells will differentiate into hepatocytes duktural. Duktural hepatocytes dinangap as transitional cell related among others to meraplasia duktural of hepatocytes parenkimal become intrahepatic biliary epithelium becomes. Conversion metaplasia of epithelium duktural into hepatocytes parenkimal. And differentiation of stem cells of the hepatocyte lineage.
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Published by press-online diva author: Putheran, AD, 2012. Hours Piket Organ Human Body. Yogyakarta: Diva Press

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